DEVELOPMENT OF A NEW ONE-EYE IMPLANT BY 3D BIOPRINTING TECHNIQUE
DOI:
https://doi.org/10.59277/RRST-EE.2023.68.2.22Keywords:
Eye implant, Digital imaging and communications in medicine (DICOM), Implant mountingAbstract
The paper analyzes the possibility of implementing a new eye implant using the 3D bioprinting technique and the experimental model underlying it. The paper includes the stages of image processing using Digital Imaging and Communications in Medicine (DICOM) and the processing of the eye implant, results, and exploitation. In the exploitation part of the eye implant, the aims are optimizing the image processing stages and refining the precision of the calibration model. In the manufacturing part, the new eye implant is fabricated with the help of machines. These machines are suitable for manufacturing structures with their porosity controlled by additive manufacturing techniques. The feasibility of using 3D printing techniques using biocompatible materials in structures with predetermined porosity was demonstrated to manufacture a customized eye implant using medical imaging Computed Tomography (CT) results. The work was performed within the OrbImplant Project.
References
(1) V. Potop, V. Coviltir, C. Corbu, M. Burcel, C. Ionescu, D. Dascalescu, Corneal hysteresis, a glaucoma risk factor independent of the intraocular pressure, Rev. Roum. Sci. Techn.– Électrotechn. Et Énerg., 64, 3, pp. 297–300 (2019).
(2) I. Stanica, F. Moldoveanu, M. Dascalu, A. Moldoveanu, G.-P. Portelli, C. Bodea, Neurorehabilitation system using virtual reality and myo armband for patients and medical personnel training, Rev. Roum. Sci. Techn.– Électrotechn. Et Énerg., 65, 1-2, pp. 139–144 (2020).
(3) N. Bentabet, N. Berrached, An efficient asynchronous brain-computer interface for assistive technology: a novel approach, Rev. Roum. Sci. Techn.– Électrotechn. Et Énerg., 65, 1-2, pp. 131–137 (2020).
(4) O. Abdulhameed, A. Al-Ahmari, W. Ameen, Additive manufacturing: challenges, trends and applications, Advances in Mechanical Engineering, 11, 2, pp. 1-27 (2019).
(5) T. Raynaa, L. Striukovab, From rapid prototyping to home fabrication: how 3D printing is changing business model innovation, Technological Forecasting and Social Change, 102, pp. 214-224 (January 2016).
(6) E. Koçak et al., Three dimensional bioprinting technology: applications in pharmaceutical and biomedical area, Colloids and Surfaces B: Biointerfaces, 197 (2021).
(7) A.C. Sommer et al., Implementations of 3D printing in ophthalmology, Graefe's Archive for Clinical and Experimental Ophthalmology, 257, pp. 1815–1822 (2019).
(8) M.J. Willemink, P.B. Noël, The evolution of image reconstruction for CT – from filtered back projection to artificial intelligence, Eur. Radiol., 29, 5, pp. 2185–2195 (2019).
(9) A. Pugalendhi et al., Design and development of model eye for retina laser by using additive manufacturing, Proc. of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 235, 1, pp. 89-98 (2021).
(10) M. Curilă, S. Curilă, C. Grava, Geometry compression for 3D models, Rev. Roum. Sci. Techn.– Électrotechn. et Énerg., 61, 2, pp. 201–204 (2016).
(11) R.D. Larochelle et al., 3D Printing in eye care, Ophthalmol. Ther., 10, 4, pp. 733-752 (2021).
(12) T.M. Shiju et al., 3D in vitro corneal models: a review of current technologies, Experimental Eye Research, 200 (2020).
(13) W. Zeng, X. Jiang, P. J. Scott, T. Li, A new method to characterize the structured tessellation surface, Procedia CIRP, 10, pp. 155–161 (2013).
(14) M. Eibl, DEViD: A media design and software Ergonomics integrating visualization for document retrieval, Information Visualization, 1, 2, pp. 139-157 (2022).
(15) M.D. Herrmann et al., Implementing the DICOM standard for digital pathology, Journal of Pathology Information, 9, 37, pp. 1-16 (2018).
(16) A.O. Hebb, A.V. Poliakov, Imaging of deep brain stimulation leads using extended Hounsfield Unit CT, Stereotactic and Functional Neurosurgery, 87, 3, pp. 155-160 (2009).
(17) R. Cadle et al., An image analysis-based workflow for 3D bioprinting of anatomically realistic retinal vascular patterns, Bioprinting, 23 (2021).
(18) J. Klimczak, S. Helman, S. Kadakia, R. Sawhney, M. Abraham, A. K. Vest, Y. Ducic, Prosthetics in facial reconstruction, Craniomaxillofac. Trauma Reconstr., 11, 1, pp. 6–14 (2018).
(19) Y. Bozkurt et al., 3D printing technology; methods, biomedical applications, future opportunities and trends, Journal of Materials Research and Technology, 1, 4, pp. 1430-1450 (2021).
(20) A.J. Sheoran et al., Bio-medical applications of additive manufacturing: a review, Procedia Manufacturing, 51, 7, pp. 663-670 (2020).
(21) L. Hodásová et al., Polymer infiltrated ceramic networks with biocompatible adhesive and 3D-printed highly porous scaffolds, Additive Manufacturing, 39 (March 2021).
(22) S. Iyer, M. Alkhader, T.A. Venkatesh, Electromechanical response of piezoelectric honeycomb foam structures, Journal of the American Ceramic Society (2013).
(23) D. Ulieru, A. Topor, X. Vila, O.M. Ulieru, Great flexibility nanomanufacturing technology concept of new ocular implant with high biocompatibility degree and fast proliferation speed, EuroNanoForum Conference, La Valletta, Malta, pp. 21-23 (2017).
(24) L.M. Popescu, R.M. Piticescu, A.M. Motoc, L.M. Voinea, S.L. Grădinaru, D. Ulieru, A. Topor, Three-dimensional structures based on hydroxyapatite and polyurethane-diol, obtained by the 3D printing technique, Invention Patent No. 132753 issued by OSIM.
